Some Aspects of a Non-linear Effect of Zinc Ions...: Abstract

	Karl und Veronica Carstens-Stiftung A Foundation for the Promotion and Support of Complementary Medicine

	Harisch G, Kretschmer M Some Aspects of a Non-linear Effect of Zinc Ions on the Histamine Release from Rat Peritoneal Mast Cells Res Comm Chem Path Pharmac. 1987: 55(1): 39-47.
Abstract	Addition of zincchloride or zincorotate to the lavage medium successfully influences the histamine release from rat peritoneal mast cells. The effect of these zinc compounds is not dosis-linear. 20 and 30 mg/l ZnCl₂ cause a rather strong, 0.5, 5 and 10 mg/l ZnCl₂ a weak depression in the release of histamine. An increase in the histamine release is caused by 40 mg/l ZnCl₂. Likewise, a similar non-dosis-linear effect, can be observed with zincorotate. Concentrations of 10 and 30 mg/l zincorotate cause a decrease of the release; 0.05, 0.1, 1 and 60 mg/l have only minimal effects; an addition of 90 mg/l leads to an increase in the histamine release. Related to the Zn²⁺ ion the effect of zincchloride and zincorotate is not equivalent.

Project	Published from project: Biochemical Basics of Homeopathy [ Details ]

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