Gezielte Immunstimulation durch eine...: Abstract

	Karl und Veronica Carstens-Stiftung A Foundation for the Promotion and Support of Complementary Medicine

	Gohla S, Neth R-D Gezielte Immunstimulation durch eine Polysaccharidfraktion aus Thuja occidentale L. tpk. 1988: 2(12): 717-725.
Abstract	The arborvitae or Thuja occidentale L. (Cupressaceae) has rarely been investigated until now. Several authors have demonstrated that allopathic and homoeopathic extracts of this plant could be used as strong antiviral agents directed against plant and animal viruses. Polysaccharide fractions have been isolated from the extract of the herbal parts of T. occidentale L. by ethanol precipitation and ultrafiltration. The Thuja polysaccharide fraction (TPS) proved to be highly mitogenic on peripheral blood leukocytes. It was demonstrated by different enrichment and staining methods that the mitogenic and cluster-forming activity of TPS cause T cell induction, in particular, of CD4+ T-helper/inducer cells as opposed to B cells. The CD4+ T-helper/inducer cell induction is connected to an increased production of IL-2. The clusterforming ability and mitogenity of TPS correlates well with the ³H-thymidine uptake. Whether it is possible to use these polysaccharide fractions as an adjuvant in the therapy of immune deficiency syndromes and cancer must now be further investigated.

Project	Published from project: The Immunmodulatory Effective Compound of Thuja occidentalis L. [ Details ]

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